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微生物发酵生产DHA的研究进展 被引量:7

Research progress in DHA production by microbes
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摘要 DHA(二十二碳六烯酸)是一种对人体重要的长链多不饱和脂肪酸,破囊壶菌科微生物因富含DHA成为当前的研究热点。本文介绍了DHA的微生物来源及其代谢途径,对国内外研究情况进行综述,详细阐述了影响DHA发酵的各种因素,并指出选育高产菌株、代谢途径分析、放大培养及转基因植物是今后工作的方向。 DHA is very long chain polyunsaturated fatty acids that provide important human health benefits. Thraustochytriales have become the current research hot spot because of its high level of DHA.In this article the sources of DHA and microbial metabolic pathways were introduced, and the international research progress on DHA were summarized.The various factors that affect DHA fermentation were also studied and it was pointed out that the future work shouJd emphasis on screening high-yielding strains and studying the metabolic pathways,the scale-up cultures,and the transgenic production DHA.
出处 《食品工业科技》 CAS CSCD 北大核心 2014年第21期395-400,共6页 Science and Technology of Food Industry
基金 福建省科技厅项目(2011H6007)
关键词 DHA 发酵 研究进展 DHA fermentation research progress
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