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二肽基肽酶-4(DPP-4)抑制剂西格列汀在2型糖尿病治疗中的作用 被引量：5

Clinical Application in Type 2 Diabetes of DPP-4 Inhibitors Sitagliptin
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摘要 目的:介绍新型口服降糖药二肽基肽酶-4(DPP-4)抑制剂西格列汀及其最新研究进展。方法 :对西格列汀的药理作用、药代动力学、不良反应及药物相互作用等方面的临床研究进行论述。结果和结论 :西格列汀是一种安全、有效的新型口服降糖药,具有良好的临床应用前景。 Objective：To introduce DPP-4 （dipeptidyl peptidase-4,DPP-4） inhibitor sitagliptin and its latest research progress.Methods：A review was conducted on clinical research of sitagliptin about its pharmacological effect,pharmacokinetic characteristics,adverse reaction and drug interaction etc.Results and Conclusion：Sitagliptin is a new safe and effective oral hypoglycemic drug,and it has a good prospect in clinical application for the treatment of type 2 diabetes.
作者 刘莹 崔向丽 刘丽宏
机构地区 首都医科大学附属北京朝阳医院药事部
出处 《临床药物治疗杂志》 2014年第5期54-58,共5页 Clinical Medication Journal
关键词 二肽基肽酶-4 (DPP-4) 西格列汀 药理作用 2型糖尿病治疗 DPP-4 inhibitor sitagliptin pharmacological effect treatment of type 2 diabetes
分类号 R977.15 [医药卫生—药品]
  • 相关文献

参考文献22

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二级参考文献27

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共引文献42

同被引文献48

  • 1赖宇明.磷酸西格列汀在老年2型糖尿病治疗中的临床应用[J].中国医药导刊,2013,15(S1):156-157. 被引量：4
  • 2杨琳,周智广,黄干,颜湘,欧阳玲莉,伍汉文.LADA患者胰岛β细胞功能的前瞻性研究[J].中华内分泌代谢杂志,2003,19(4):263-266. 被引量：30
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引证文献5

二级引证文献10

临床药物治疗杂志
2014年 第5期

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