基于HIS真实世界异位妊娠发病特点及证治规律分析

Pathogenic characteristics and syndrome treamment rules analysis of ectopic pregnancy based on the HIS of the “real world”

目的：了解异位妊娠发病特点及证治规律,为临床合理用药和治疗方案的制定提供参考。方法：基于全国15家三甲医院异位妊娠患者的HIS数据,用频数统计及关联规则进行分析。结果：异位妊娠患者年龄中位数为30岁,急诊入院占29.14%,入院病情危急的占31.15%,住院1-7 d,医保比例逐年增加,住院费用大多在5000-10000元;中医证候中气虚血瘀型占51.66%,气滞血瘀型占37.09%;常见合并症为盆腔良性肿物、慢性盆腔炎、慢性输卵管炎;常见并发症为贫血、盆腹腔出血、休克;发病部位以输卵管妊娠最多占96.52%;使用频率最高的前5类西药依次为抗生素类药、止血药、杀胚药、纠正贫血药、保肝药;使用频率最高的前5类中药依次为补气血类、活血化瘀、清热解毒、理气、祛湿。结论：异位妊娠患者危急症较多,部位多发生在输卵管,中医证型多为气虚血瘀型和气滞血瘀型。

Objective： To describe ectopic pregnancy patients＇ clinical character,the TCM Syndrome and treatment regular based on analyzing hospital information system. Method： We collected HIS data from 15 third grade hospitals,and integrated the data to a data warehouse. Descriptive statistic methods and association rules were used in analysis of the data. Result： By analysis 4641 cases of ectopic pregnancy,we found that the median age is 30 yeays old. Most patients＇ hospital admission days was within 7days,hospitalization expenses was in the range of 5000 - 10000 yuan. Emergency patients account for 29. 14%,critical patients account for 29. 14%. 96. 52% of the patients are tubal pregnancy. The top three complicatig disease are pelvic benign tumor,pelvic inflammation and chronic salpingitis. About syndrome of TCM,qi deficiency and blood stasis is 51. 66%,qi stagnation and blood stasis syndrome is 37. 09%. Chinese and western medicine treatment have a certain rule. Conclusion： Most ectopic pregnancy are tubal pregnancy. Emergency patients and critical patients account for high proportion. Qi deficiency and blood stasis,qi stagnation and blood stasis syndrome are most common in ectopic pregnancy patients,medicine choice ought to be based on syndromes of TCM.