经桡动脉行冠状动脉斑块旋磨和药物支架置入术治疗严重钙化病变的安全有效性

Safety and efficacy of rotational atherectomy followed by drug-eluting stents implantation via the transradial approach in complex calcified coronary lesions

目的:探讨经桡动脉行冠状动脉斑块旋磨术和药物洗脱支架置入术,治疗严重钙化病变的临床效果。方法:回顾性分析我院2010年1月至2011年1月,经桡动脉行冠状动脉斑块旋磨术和药物洗脱支架置入术,冠心病患者的89例临床资料。并分析其手术特点、并发症及主要不良心血管事件(包括全因死亡、非致死性心肌梗死、靶血管血运重建)。结果:89例(100%)患者均成功经桡动脉行冠状动脉斑块旋磨术,并置入药物洗脱支架。术中共有8例(9.0%)患者发生并发症,经处理后取得良好的效果。术后随访(22.21±4.73)个月,主要不良心血管事件的发生率为12.4%。结论:经桡动脉行冠状动脉斑块旋磨术和药物洗脱支架置入术,治疗严重钙化病变是一种安全、有效的治疗方法。

Objective：To evaluate the clinical outcomes of rotational atherectomy followed by drug-eluting stenting via the transradial approach in heavily calcified coronary lesions. Methods： From January 2010 to January 2011,89 consecutive patients with heavily calcified coronary lesions underwent rotational atherectomy and drug-eluting stenting via transradial approach in our hospital were retrospectively enrolled. Procedure parameters,complications and major adverse cardiovascular events（ all cause death,non-fatal myocardial infarction,target vessel revascularization） were analyzed. Results： All 89 patients were successfully treated with rotational atherectomy and drug-eluting stents implantation. Eight cases（ 9. 0%） developed complications and were treated accordingly during procedure with satisfactory results. During a median follow-up period of 22 months,the incidence of major adverse cardiovascular events was 12. 4%. Conclusion： Rotational atherectomy followed by drug-eluting stenting via transradial approach is safe,effective technique for treating heavily calcified coronary lesions.