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瑞舒伐他汀对NSTEMI患者血浆Hcy、Hs-CRP、N-pro-BNP水平的影响

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摘要 目的评价瑞舒伐他汀对非ST段抬高心肌梗死(NSTEMI)患者血浆同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)和N末端B型脑钠肽前体(NT-pro-BNP)水平的影响。方法将60例NSTEMI患者随机分为治疗组和对照组各30例。对照组给予阿司匹林、氯吡格雷抗血小板聚集及低分子肝素抗凝治疗;治疗组在对照组治疗基础上予瑞舒伐他汀10 mg口服,每晚1次,2周后观察治疗前后血清Hcy、hs-CRP、NT-pro-BNP水平的变化并随访3个月后心血管事件发生情况。结果与对照组相比,治疗2周后血清Hcy、hs-CRP、NTpro-BNP水平均明显下降,差异有统计学意义(P<0.05)。随访3个月治疗组总心血管事件发生率明显低于对照组,差异有统计学意义(P<0.05)。结论瑞舒伐他汀可以提高NSTEMI的疗效,能降低血中Hcy、hs-CRP、NT-pro-BNP水平,有利于NSTEMI患者的恢复。
出处 《中国医药指南》 2014年第30期150-151,共2页 Guide of China Medicine
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