经尿道前列腺电切术与双极等离子切除术治疗前列腺良性增生的疗效比较

The Comparison of Effect of Transurethral Electric Resection of the Prostate and Transurethral Bipolar Plasma Resection of the Prostate in the Treatment of Benign Prostate Hyperplasia

目的比较经尿道前列腺电切术(TURP)和经尿道双极等离子前列腺切除术(PKRP)治疗前列腺良性增生(BPH)的临床疗效及安全性。方法将2009年10月至2013年2月解放军180医院泌尿外科收治的142例BPH患者根据随机数字表法分为TURP组70例和PKRP组72例,比较两组手术相关指标,国际前列腺症状评分(IPSS),术后尿流率峰值(Qmax)、生活质量评分(QOL)和剩余尿量(RUV)。结果 PKRP组术中出血量、膀胱冲洗时间、留管时间及住院时间均显著少于TURP组(P<0.05),两组手术时间及术后并发症发生率比较差异无统计学意义(P>0.05);两组治疗后IPSS、QOL、Qmax及RUV均较治疗前明显好转(P<0.05),且PKRP组IPSS、QOL、Qmax改善更为显著(P<0.05)。结论 PKRP与TURP均是治疗BPH的有效手术措施,但PKRP术中出血量较少,疗效更佳,值得临床推广应用。

Objective To compare the clinical efficacy and safety of T URP and PKRP in the treatment of benign prostate hyperplasia（BPH）.Methods A total of 142 patients with BPH treated in Department of Urology of PLA NO.180 from Oct.2009 to Feb.2013 were included in the study,who were divided into the TURP group（n =70） and PKRP group（n =72） according to the random number table method.The indicators related to the operation,the international prostate symptom score（IPSS）,peak postoperative urinary flow rate（Qmax）,quality of life score（QOL） and residual urine volume（RUV） of the two groups were compared.Results The bleeding amount,bladder washing time,indwelling catheter time and hospital stay of PKRP group were significantly lower than that of TU RP group（P ＜ 0.05）,and the operation time and postoperative complications of the two groups had no significant difference（P ＞ 0.05）.The IPSS,QOL,Qmax and RU V of the two groups after treatment were significantly improved（P ＜ 0.05）,and the IPSS,QOL and Qmax of PKRP group improved more significantly（P ＜ 0.05）.Conclusion PKRP and TURP are both effective surgeries for treatment of BPH,while PKRP has less intraoperative blood loss and better curative effect,thus is worth of clinical application.