期刊文献+

心力衰竭患者QRS波时限与血浆脑利钠肽(BNP)的相关性研究

The Investigation of the Correlation between Electrocardiogram QRS Duration and Plasma B-type Natriuretic Peptide in Patients with Heart Failure
下载PDF
导出
摘要 目的探讨心力衰竭患者心电图QRS波宽度与血浆脑利钠肽(BNP)的相关性,评价其判断心力衰竭患者的临床心功能的预测价值。方法根据心力衰竭诊断标准(Framingham标准),入选152例患者,明确诊断为心力衰竭。152例患者分别测定心电图的QRS的时限、血浆BNP、左室舒张末径(LVDD)及左室射血分数(EF),并根据QRS的时限分为正常组及异常组(增宽≥120 ms),数据进行统计分析。结果 QRS时限正常组中脑利钠肽与QRS的时限异常组中脑利钠肽两两相比较有显著性差异。结论宽QRS(时限≥120 ms)心力衰竭患者的心力衰竭程度明显高于QRS正常者,用于评价心力衰竭患者病情有一定的临床意义。 Objective To explore the relationship between electrocardiogram QRS duration and plasma B-type natriuretic peptide (BNP) in patients with heart failure. To evaluate the predictive value of QRS duration on clinical heart function in patients with heart failure. Methods According to the diagnostic standard of heart failure (Framingham standard), electrocardiogram QRS duration, plasma B-type natriuretic peptide (BNP), left ventricular end diastolic diameter (LVDD), and left ventricular ejection fraction (EF) were measured in 152 patients with heart failure. Then, according to QRS duration, 152 patients with heart failure were divided into normal group and abnormal group (QRS duration≥120 ms). Finally, we conducted statistical analysis of data. Results BNP was signiifcantly different between normal group and abnormal group. Conclusion The heart function classiifcation of wide QRS (QRS duration≥120 ms) is signiifcantly higher than that of normal QRS in patients with heart failure. QRS duration has the certain clinical signiifcance in evaluation of heart failure patients.
出处 《中国医药指南》 2014年第29期50-51,共2页 Guide of China Medicine
关键词 心力衰竭 血浆脑利钠肽(BNP) 左室舒张末径(LVDD) 左心室射血分数(EF) Heart failure Electrocardiogram QRS Plasma B-type natriuretic peptide(BNP) Left ventricular end diastolic diameter(LVDD) Left ventricularejection fraction(EF)
  • 相关文献

参考文献9

  • 1陈灏珠,林果为.实用内科学[M].13版.北京:人民卫生出版社,2009:919.
  • 2Azzazy HM,Christenson RH.B-type natriuretic peptide:physiologic role and assay charaeteristics[J].Heart Fail Rev,2003,8(4):315-321.
  • 3Mukoyama M,Nakao K,Saito Y, et al.Human brain natriuretic peptide,a novel cardiac hormone[J].Laneet,1990,335(8692):801-802.
  • 4耿国英,毛磊,吴雷.有关脑钠肽与心力衰竭的探讨[J].医学信息(中旬刊),2010,5(2):215-216. 被引量:2
  • 5陈海坚,魏芝宝,邓红胜,黄宇翔,张灿,孙喜文,陈亦明,黄之文.脑钠肽测定在心力衰竭诊断中的临床应用[J].中国现代医生,2008,46(30):7-8. 被引量:11
  • 6任琼,张晓刚.宽QRS与超声心动图心室结构改变的关系[J].心血管病学进展,2010,31(4):609-611. 被引量:5
  • 7Pcnicka M,Bartanek J.Improvement of left ventricular function therapy is predicted by tissve Doppler maging echocardiography[J].Circulation,2004,109(8):978-983.
  • 8Shenkman HJ,Pampati V, Khandelwal AK, et al.Congestive heart failure and QRS duration establishing prognosis study[J].Chest,2002, 122(2):528-534.
  • 9Yu CM,Fung WH,Lin H,et al.Predictors of left ventricular reverse remodeling after cardiac resynchronization therapy for heart failure secondary to idiopathic dilated or ischemic cardiomyopathy[J].Am J Cardiol,2003,91(6):684-688.

二级参考文献30

  • 1肖志辉.脑钠肽对首发急性心肌梗死近期预后的评价[J].中国医药导报,2007,4(02X):103-103. 被引量:6
  • 2付潮胜,张松,陈澍.脑利钠肽评估急性心肌梗死预后的病例对照观察[J].现代实用医学,2007,19(2):111-112. 被引量:1
  • 3[1]Packer M,Cohn J.Consensus recommendations for theman-agementof chronic heart failure.On behalf of the member-ship of the advisory council to improve outcomes nationwide in heart failure[J].Am J Cardiol,1999,83(2A):1A.
  • 4[2]Grantham JA,Borgeson DD,Burnett JC J.BNP:Pathophysiological and potential trerapertic roles in acute congestive heart failure[J].Am J physiol,1997,272(4 Pt2):R1 077.
  • 5[3]Sudoh T,Kanyawa K,Minsmino N,et al.A natriureticpeptide in porcine brain[J].Nature,1988,322:78-81.
  • 6[4]Shapiro BP,Chen HH,Burnett JCJ,et al.Use of plasma brain nauinretic peptide concentration to aid in the diagnosis of heart failure[J].Mayo Clin Proc,2003,78:481-486.
  • 7[5]Collins SP,Ronan-Bentle S,Storrow AB.Diag-nostic and prognostic usefulness of natriuretic peptides inemergency department patients with dyspnea[J].Ann Emerg Mad,2003,41:532-545.
  • 8[7]Tjeerdsma G,De Boer RA,Boomsma F,et al Rapid bedside measurement of brain natriuretic peptide inpatients with chronic heart failure[J].Int J Cardiol,2002,86:143-149.
  • 9[8]Groenning BA,Nilsson JC,Sondergaard L,et al Evaluation of impaired left ventriculer ejection fraction and incrcased dimensions by multiple neurohumoral plasma concentrations[J].European Journal of Heart Failure,2001,3:699.
  • 10[9]De Lemos JA,Mc Guire DK,Drazer MH.B-type natriuretic peptide in cardiovascular disease[J].Lancet,2003,362:316-322.

共引文献705

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部