醒脑静注射液治疗急性重度酒精中毒的临床观察

Clinical observation of Xingnaojing Injection in the treatment of acute severe alcoholism.

目的：探讨醒脑静注射液治疗急性重度酒精中毒的临床疗效。方法：将我院确诊的165例酒精中毒患者随机分为3组，每组55例，A组常规支持治疗，B组在常规支持治疗的基础上给予纳洛酮，C组在常规支持治疗的基础上给予醒脑静，观察各组患者的显效和痊愈时间，并比较各组患者的意识清醒、能正确回答问题以及能够独立行走的时间，以及药物的不良反应等临床治疗效果。结果：C组患者的显效时间和痊愈时间均短于A、B（P〈0．05）；C组患者的意识清醒时间、能正确回答问题时间以及能够独立行走时间也均短于A、B组，其差异均有统计学意义（P〈0．05）。结论：醒脑静治疗急性重度酒精中毒的临床疗效满意，有效缓解临床症状，缩短病程，促进苏醒，并在呕吐、恶心等并发症的发生上得到了很好的控制，具有临床应用价值，值得推广使用。

Objective ： To investigate the clinical effect of Xingnaojing Injection in the treatment of acute severe alcoholism. Methods： 165 cases of alcohol poisoning patients in our hospital were randomly divided into 3 groups, 55 cases in each group, A group of conven- tional treatment, B group was given naloxone based on conventional supporting treatment, C group were given XJngnaojing based on con- ventional supporting treatment, observed in patients with response and recovery time, and compared between groups of patients conscious, to be able to answer the question correctly and can walk independently of the time, and side effects of drugs in clinical treatment effect. Results： Group C patients onset time and recovery time were shorter than the A, B （ P 〈 0.05 ） ; group C patients conscious of time, to be able to answer the question correctly and in time to walk time was shorter than the A, the B group, which were statistically significant （ P 〈0. 05 ）. Conclusion：Clinical effect of Xingnaojing Injection in treating acute severe alcoholism satisfaction, could effectively relieve the clinical symptoms, shorten the course of disease, promote recovery, and obtained good control in vomiting, nausea and other complications, has clinical application value, might be worthy to be popularized.