孟鲁司特片辅助治疗小儿毛细支气管炎50例的临床效果

Investigate monostele auxiliary treatment of children with capillary bronchitis curative effect and safety

目的：探讨孟鲁司特片辅助治疗小儿毛细支气管炎的疗效及安全性。方法：将100例3—14个月的毛细支气管炎患儿随机分为治疗组和对照组，2组均采用综合治疗包括吸氧、雾化止咳、强心利尿、镇静等，同时给予热毒宁注射液0．6ml／kg加入5％葡萄糖100ml静脉滴注，每天1次，治疗组在综合治疗的基础上加用孟鲁司特片4mg，每晚1次口服。对治疗前后患儿症状、体征持续时间、气道阻力参数进行比较。结果：治疗组在治愈率方面明显高于对照组，在缓解喘憋、缩短哮鸣音及咳嗽持续时间、住院天数方面均明显短于对照组（P〈0．05）。结论：孟鲁司特片辅助治疗小儿毛细支气管炎，可缩短病程，改善肺功能，疗效确切，且方便、安全，可作为辅助治疗小儿毛细支气管炎的主要药物。

Objective ：To investigate the monostele auxiliary treatment of children with capillary bronchitis curative effect and safety.Methods ： 100 cases of 3 - 14 months of bronchiolar were randomly divided into treatment group and control group, two groups were treated with comprehensive therapy including oxygen, aerosolized cough, cardiac diuretic, sedative, but given the Dunning Injection 0.6 mi/kg in 5% glucose 100 ml intravenous drip, once per day, foundation treatment group; in the comprehensive therapy combined with monostele tablets 4 mg, orally 1 times every night. To compare before and after treatment in children with symptoms and signs, duration, airway resistance parameters. Results：The cure rate in treatment group was significantly higher than the control group, in relieving asthma, wheeze and cough and shorten hospitalization duration, were significantly shorter than the control group （ P〈0.05 ）. Conclusion： special auxil- iary bronchiolar treatment of monostele, can shorten the course of disease, improve lung funetion, curative effect might be exact, conven- ient and safe, the main drugs could be used as an auxiliary treatment of children with bronchiolar.