急性脑梗死患者微栓子监测与颈动脉硬化的相关性分析

Relationship between micro emboli in patients with acute cerebral infarction and carotid atherosclerosis

目的探讨急性脑梗死患者微栓子监测与颈动脉硬化的关系。方法选取我院2013-01—2013-12收治的60例急性缺血性脑血管病患者为研究组,并选取同期60例非急性缺血性脑血管病患者为对照组,对2组患者实施经颅多普勒微栓子监测。结果研究组微栓子阳性率40.0%,对照组为38.3%,2组比较差异无统计学无意义(P>0.05);微栓子阳性患者颈动脉斑块发生率59.6%(28/47),微栓子阴性患者39.7%(29/73),2组比较差异有统计学意义(P<0.05)。微栓子阳性患者不稳定颈动脉斑块发生率96.4%(27/28),微栓子阴性患者为51.7%(15/29),2组比较差异有统计学意义(P<0.05)。结论微栓子监测对指导和预防颈动脉硬化的急性脑梗死患者具有较好的效果,具有一定的应用价值。

Objective To investigate the relationship between clinical monitoring of micro-emboli in acute cerebral infarc-tion and carotid atherosclerosis. Methods 60 patients with acute ischemic cerebrovascular disease from January 2013 to Decem-ber 2013 were selected as the study group ,60 patients without ischemic cerebrovascular disease were selected as the control group during the corresponding period. Tran cranial Doppler was used to monitor micro-emboli in Patients of the two groups.Results The micro emboli positive rate of study group was 40.0% , the micro emboli positive rate of control group was 38.3% ,there was no significant difference in the positive rate of micro-emboli between study group and the control group （P〉0.05）. The positive rate of carotid artery plaque in patients with positive micro-emboli was 59.6% （28/47） ,while that in pa-tients with negative micro emboli was 39.7% （29/73）;Data of the two groups have statistically significant difference （P〈0.05）. The positive rate of unstable carotid plaques in patients with positive micro emboli was 96.4% （27/28） while that in pa-tients with negative micro-emboli was 51.7% （15/29）;the difference of data between two subgroups was statistically signifi-cant （P〈0.05）.Conclusion Monitoring micro-emboli has important significance in the instruction of prevention and treatment of acute ischemic cerebrovascular disease in patients with carotid plaques and has a certain value in clinical application.