痉挛型脑瘫患儿发病的相关因素研究

Analysis of related disease factors of children with cerebral palsy spastic

目的探讨痉挛型脑瘫患儿发病的相关因素。方法收集我院2009-06—2013-06就诊的痉挛型脑瘫患儿89例为研究对象。通过问卷调查获取相关信息,分析痉挛型脑瘫患儿发病与遗传因素、环境因素、孕期母亲因素及新生儿因素的关系。结果新生儿出生体质量、母亲学历、出生时的肌张力、皮肤颜色、孕妇是否经历过严重刺激、居住环境、孕期是否使用过解热镇痛药、孕期是否阴道出血、出生时是否有颅内出血、是否有出生窒息及是否有宫内窘迫这11项因素与痉挛型脑瘫的发生有关。结论遗传因素、环境因素、孕期母亲因素及新生儿因素与痉挛型脑瘫发生均有密切的关系,为减少脑瘫的发生加强孕产期的保健及新生儿的管理非常有必要。

Objective To investigate the related disease factors of children with cerebral palsy spastic.Methods 89 chil-dren with spastic cerebral palsy from June 2009 to June 2013 in our hospital were collected and considered as the research ob-ject. The patient’s information was obtained by a questionnaire survey. The relationship between the morbidity of children with spastic cerebral palsy and the genetic factors ,environmental factors ,neonatal factors and maternal factors during pregnan-cy.Results The occurrence of children with spastic cerebral palsy had a correlation with the following factors ：the skin color , weight and muscle tone of neonate at birth ,maternal education and living environment ,whether pregnant women experiencing serious stimulation and vaginal bleeding and using antipyretic analgesics ,and whether neonate having intracranial hemorrhage , birth asphyxia and fetal distress. Conclusion Genetic and environmental factors ,maternal condition during pregnacy and neo-natal factors have close relationship with children with spastic cerebral palsy. Strengthening the health care during pregnancy and neonatal nursing are very necessary in decreasing the incidence rate of children with spastic cerebral palsy.