90例类百日咳临床特征分析

The Clinical Characteristics and Outcome of Children with Pertussis-like syndrome

目的:了解儿童类百日咳的临床特征和转归。方法:收集2012年6月-2013年6月在郑州市儿童医院治疗的90例类百日咳患儿的病例资料。结果:6个月以下婴儿占63例(70%),50例患儿行上消化道造影检查,其中43例(86%)合并有胃扭转及胃食道返流等。所有患儿均给予大环内酯类抗生素治疗,87例患儿缓解出院,3例患儿好转自动出院。结论:类百日咳多为病毒与细菌混合感染所致,多见于6个月以下婴儿,对于治疗效果不理想的患儿,应重视合并胃扭转及胃食道返流的可能性,注意合理喂养方式及体位。

Objective：To study the clinical characteristics and outcome of children with Pertussis-like syndrome. Method：90 clinical data were collected from children with Pertussis-like syndrome from June 2012 to June 2013 in children’s hospital of Zhengzhou. Result：63（70%）of the 90 patients were infants aged less than 6 months. Gastric volvulus and gastroesophageal reflux was detected in 43（86%）of the 50 children with upper gastroenterography. All patients were treated with macrolide antibiotics and survived. Conclusion：This study indicate that Pertussis-like syndrome is caused by mixed infection of bacterium and virus. Most of them are infants aged less than 6 months. For the children without ideal treatment,the possibility of gastric volvulus and Gastroesophageal reflux are considered and exercised the most appropriate feeding.