摘要
目的探讨疏肝解郁中药对患有肝郁型ICPP的女童中医症候、性激素水平与心理行为的影响。方法回顾性分析门诊治疗的45例患有ICPP的女童,所有患儿均采用疏肝解郁中药进行治疗,比较治疗前后患儿的中医症候评分与性激素水平以及临床症状的变化情况。结果患有肝郁型ICPP的女童治疗后的中医症候评分(11.3±2.8)显著低于治疗前(18.2±4.7),FSH、LH、E2等性激素(3.1±0.8)、(1.1±0.3)、(11.2±2.7)水平明显低于治疗前(4.2±1.2)、(2.0±0.5)、(19.2±4.5)(均P<0.01),乳房大小、乳房直径、乳房疼痛、阴道分泌物(1.42±0.45)、(1.03±0.37)、(0.66±0.23)、(0.84±0.31)等临床症状明显优于治疗前(2.08±0.67)、(1.86±0.54)、(1.12±0.45)、(1.33±0.51)(均P<0.01)。结论疏肝解郁中药能显著减轻患有ICPP女童的中医症候评分和性激素水平,还可有效消除患儿的临床体征,是一个具有较高临床应用价值的药物。
Objective To explore the clinical effect of Shugan Jieyu medicine on the TCM syndrome, sexual hormone level and psychological behavior of female children with stagnation of liver qi type ICPP. Methods The clinical data of 45 female children with ICPP treated in outpatient were analyzed retrospectively. All of them were treated with Shugan Jieyu medicine. The TCM syndrome, sexual hormone level and clinical signs of them before and after treatment were compared. Results After treatment, the TCM syndrome score （11.3±2.8） of female children with stagnation of liver qi type ICPP was significantly lower than that of prior treatment （18.2±4.7）, the level of sexual hormone （FSH, LH, E2） （3.1±0.8）, （1.1±0.3）, （11.2±2.7） was significantly lower than that of prior treatment （4.2±1.2）, （2.0±0.5）, （19.2±4.5）, respectively（all P〈0.01）, breast size, diameter of breast, breast pain, vaginal secretions （1.42±0.45）, （1.03±0.37）, （0.66±0.23）, （0.84±0.31） was significantly better than that of prior treatment （2.08±0.67）, （1.86±0.54）, （1.12±0.45）, （1.33±0.51）, respectively （all P〈0.01）. Conclusion Shugan Jieyu medicine could reduce the TCM syndrome, sexual hormone level in female children with stagnation of liver qi type ICPP effectively, as well as eliminate the clinical signs of the patients, so Shugan Jieyu medicine is a drug with high application value in the treatment of ICCP.
出处
《中外医疗》
2014年第24期1-2,共2页
China & Foreign Medical Treatment
