抗菌肽作为饲料添加剂的研究进展

Progress of Antimicrobial Peptides as Feed Additive

抗菌肽是生物体抵抗外界病原体侵袭而产生的一类小分子活性多肽,是生物体内先天性防御系统的重要组成部分。抗生素污染问题是目前影响我国畜牧与水产养殖业可持续健康发展的重大科技问题,由此引起的养殖产品中违禁抗生素残留成为制约我国出口创汇和食品安全的瓶颈,饲料中大量添加抗生素是导致抗生素超标的主要原因之一。寻找能够替代抗生素的环保型饲料添加剂,研制出无抗生素的环境友好型饲料,是我国畜牧与水产养殖业健康发展的迫切需求。就抗菌肽的来源,不同功能以及作为饲料添加剂在养殖中的应用作一简要综述。。

Antibacterial peptides or Antimicrobial peptides （ AMPs ） , a class of small-molecule active peptides, are an important component of the innate defense system of organism to resist against invasion of foreign pathogens. Antibiotics pollution is one of the most important issues that would affect the sustainable development of stock farming and aquaculture industry in our country. Antibiotic residues in agricultural （ including aquaculture ） products involved in this issue is the bottleneck of our food safety and exports, and excessive antibiotics addition to feedstuff is one of the main reasons for antibiotic residues. Thus, finding and developing alternatives for antibiotics is the urgent requirement of healthy development of animal husbandry and aquaculture industry in China. In this article,the sources, function and its application as feed additives in livestock were reviewed..