摘要
目的:探讨妥洛特罗贴剂在儿童咳嗽变异性哮喘(CAV)治疗中的作用。方法:选取该院儿科门诊收治的113例CAV患儿随机分为治疗组55例,对照组58例。对照组给予常规治疗:口服抗组胺药、白三烯受体拮抗剂,按病情需要使用祛痰、抗感染药物;治疗组除常规治疗外,每晚睡前外贴妥洛特罗贴剂,比较两组患儿夜间咳嗽症状及症状体征消失的时间。结果:治疗组患儿夜间咳嗽症状及治疗时间情况明显优于对照组,差异有统计学意义(P<0.01)。结论:妥洛特罗贴剂在控制夜间咳嗽症状和缩短治疗时间上疗效显著,使用方便,不良反应少。
Objective: To explore the effect of tulobuterol patch in treatment of cough variant asthma (CAV) in children. Meth- ods: A total of 113 CAV children treated in outpatient department of the hospital were selected and randomly divided into treatment group (55 children) and control group (58 children) ; the children in control group were treated with conventional therapy, including oral adminis- tration of antihistamines and leukotriene receptor antagonist, expectorant and anti - infection drugs were also used if necessary; the children in treatment group were treated with conventional therapy combined with tulobuterol patch before sleep; the disappearance time of nighttime coughing, symptoms and signs in the two groups were compared. Results : The disappearance time of nighttime coughing and treatment time in treatment group were better than those in control group, there were statistically significant differences ( P 〈 0.01 ) . Conclusion : Tu- lohuterol patch can control nighttime coughing and shorten treatment time in treatment of CAV, the curative effect is significant, and the method is simple, the adverse reactions are few.
出处
《中国妇幼保健》
CAS
北大核心
2014年第31期5184-5185,共2页
Maternal and Child Health Care of China