基于高荧光碳纳米粒子的Fe^(3+)超灵敏检测

Highly Fluorescent Carbon Nanoparticles for Sensitive Detection of Iron (Ⅲ)

以廉价的豆腐残渣为碳源,用简单的水热合成法,在不同的温度下成功制备了水溶性的发射蓝光的碳纳米粒子(Carbon nanoparticles,CNPs)。通过AFM、Uv-vis、FTIR、NMR、XPS及荧光光谱对碳纳米粒子的结构和光学性能进行了研究。实验结果表明,随着制备温度升高,CNPs的荧光量子产率(Quantum yield,QY)增加,当温度达到240℃时,QY可达15.24%。该CNPs荧光探针对Fe3+的检测表现出了良好的灵敏度和选择性,检测限低至50 nmol/L。同时,CNPs荧光探针能够实现真实水样及细胞内Fe3+的检测,在传感及生物成像领域具有潜在的实际应用价值。

A simple preparative strategy was proposed for the preparation of water-soluble, bright blue-emitting carbon nanoparticles （ CNPs ） at different temperatures by hydrothermal treatment using bean curd residue as carbon source for the first time. When the temperature reaches 240 ℃, quantum yield （ QY） can be up to 15. 24%. Most importantly, such fluorescent CNPs can be served as an effective sensing platform for label-free sensitive and selective detection of Fe3＋ions with a detection of limit as low as 50 nmol/L, which is nearly 2 orders of magnitude lower than the maximum level of Fe3＋ions in the drinking water permitted by the European Community. These outstanding properties give promising potential for reliable detection of Fe3＋ in intracellular fluid and water samples, even bioimaging and optical imaging without being hazard in the future.