摘要
目的研究2型糖尿病患者行胃转流术前后肠道菌群是否发生变化。方法收集30例2型糖尿病患者术前和术后粪便,测肠道菌群,以25例健康志愿者的粪便为对照组。结果 2型糖尿病患者的肠杆菌较健康人增多,双歧杆菌较正常人减少,胃转流术后双歧杆菌增加,肠杆菌减少。结论 2型糖尿病患者出现肠道菌群失调,胃转流术后控制了血糖,双歧杆菌数量增加。
Objective To research changes of intestinal flora in patients with type 2 diabetes（ T2DM） before and after Gastric Bypass（ GBP）. Methods The feces samples of 30 patients with T2 DM before and after GBP were collected,then intestinal flora were measured; Samples of 25 healthy volunteers were used as the controls. Results Compared with healthy volunteers,E. coli in patients with type 2 diabetes increased while Bifidobacterium decreased. After accepted GBP,Bifidobacterium in T2 DM patients increased and E. coli decreased. Conclusion Patients with T2 DM occurred enteric dysbacteriosis. Gastric Bypass can control blood glucose and result in Bifidobacterium increase.
出处
《中国微生态学杂志》
CAS
CSCD
2014年第10期1146-1147,共2页
Chinese Journal of Microecology
基金
黑龙江省自然基金(D201127)
关键词
2型糖尿病
胃转流术
肠道菌群
Type 2 diabetes
Gastric bypass
Intestinal flora
