尿毒清颗粒配合结肠透析治疗慢性肾功能衰竭疗效观察

Curative effect observation on uremic clearance granule combined with colon dialysis in the treatment of chronic renal failure

目的 观察尿毒清颗粒配合结肠透析治疗对慢性肾功能衰竭（chronic renal failure,CRF）早中期患者的临床疗效.方法 收集我院76例慢性肾功能衰竭早中期患者,随机分为对照组和治疗组各38例.对照组行常规结肠透析,治疗组在常规结肠透析治疗基础上加用尿毒清颗粒保留灌肠,两组患者均行3疗程治疗.两组患者在第一次治疗前及最后一次治疗后检测血尿素氮（BUN）、血肌酐（Scr）、血尿酸（UA）.结果 治疗组和对照组BUN、Scr、UA较治疗前明显下降,治疗组的下降幅度较对照组明显,两组间差异有统计学意义（P＜ 0.05）.结论 尿毒清颗粒配合结肠透析治疗慢性肾功能衰竭患者临床疗效优于常规结肠透析,尿毒清颗粒保留灌肠在慢性肾功能衰竭结肠透析治疗中具有优势.

Objective To observe the clinical efficacy of uremic clearance granule combined with colon dialysis in the treatment of chronic renal failure （CRF） at early and middle stages.Methods 76 cases of CRF in early and middle stage in our hospital were randomly divided into control group and treatment group,two groups underwent 3 courses of treatment.38 cases of the control group,were given routine colon dialysis,38 cases in the treatment group,based on the conventional colon dialysis therapy,were added with uremic clearance granule retention enema.We observed and analyzed the patients of two groups before the first treatment and after the last treatment,detecting the blood urea nitrogen （BUN）,serum creatinine （SCr）,blood uric acid （UA）.Results In the treatment group and the control group after treatment,the BUN,SCr,UA significantly decreased compared with those before treatment,the treatment group decreased significantly compared with that of the control group,showing a significant difference between two groups （P ＜ 0.05）.Conclusion Uremic clearance granule combined with colon dialysis in the treatment of CRF patients has better clinical curative effect than the conventional colon dialysis,uremic clearance granule retention enema on CRF treated with colon dialysis has its advantages.