大学生腹型过敏性紫癜15例临床分析

Clinical analysis of 15 college students with abdominal type allergic purpura

目的探讨大学生腹型过敏性紫癜的临床特点。方法对2008年9月至2014年3月本院收治的15例腹型过敏性紫癜的临床特点进行回顾分析。结果 15例患者均有腹部绞痛,腹痛部位不固定,症状严重,腹部体征轻微。其中,5例伴有恶心、呕吐,7例有便血,15例便潜血均为阳性。腹痛发生后1~5 d出现双下肢紫癜。内镜表现为胃肠黏膜有广泛出血、糜烂、溃疡。解痉和抗酸药物治疗无效,抗过敏药物和糖皮质激素治疗有效。结论大学生腹型过敏性紫癜有胃肠黏膜广泛出血点,腹痛症状严重,腹部体征轻微,胃肠黏膜有特殊内镜表现。抗过敏药物和糖皮质激素治疗效果好。

Objective To discuss the clinical characteristics of abdominal type allergic purpura of college students. Methods The clinical characteristics of 15 cases of abdominal type allergic purpura were retrospective analyzed from 2008 September to 2014 March. Results All the 15 patients had abdominal colic. The abdominal pain location was not fixe6 Their symptoms were severe hut sighs were slight. Among them, 5 patients were accompanied by nausea, vomiting, 7 had hematochezia, and all were positive in fecal occult blood. Purpura occurred in both lower limbs 1 to 5 days after the occurrence of abdominal pain. Endoscopic manifestations were extensive bleeding, erosion, and ulcer of gastrointestinal mucosa. Antispasmodic and anti acid drugs were invalid. Antiallergic drugs and glucocorticoid therapy were effective. Conclusions The clinical characteristics of abdominal type allergic purpura of college students are extensive bleeding of gastrointestinal mucosa, severe abdominal colic but slight sighs, special endoscopic findings of gastrointestinal mucosa. Anti allergic drugs and glucocorticoid therapy are valid.