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固载脯氨酸的毛发状纳米粒子的合成及其应用研究 被引量：1

Synthesis and application research of hairy nanoparticle supported proline
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摘要 毛发状粒子表面的聚合物链是一个具有一定流动性的动态体系,其负载的催化剂综合了均相和非均相负载催化剂的优点,为手性催化剂的负载和实用化提供了一条新的途径。本文利用Si O2纳米粒子表面修饰制得的功能基,通过表面RAFT聚合,并经过氨基去保护后制得负载脯氨酸的毛发状纳米粒子。通过热重、红外和透射电镜对毛发状二氧化硅纳米粒子的结构进行表征,并将获得的毛发状纳米粒子作为催化剂直接催化不对称Aldol反应。 The polymer brushes on the surface of hairy nanoparticles are a dynamic system possessing a certain degree of mobility,so hairy particles supported catalysts can combine the advantages of both homogeneous catalysts and heterogeneous catalysts,andprovide a new and practical way for chiral catalyst load. Based on above,the hairy nanoparticles supported proline were synthesizedby surface-initiated RAFT polymerization from silica initiator particles. The structure and composition of the hairy nanoparticles obtainedwere characterized by Fourier transform infrared spectrum（FTIR）,thermogravimetric analyzer（TGA）and transmission electronmicroscope（TEM）. Futhermore,the achieved hairy nanoparticles were used in asymmetric direct Aldol reaction as catalysts.
作者 李新娟 杨蓓蕾 陈茂钦 武大中 周勇 胡志国
机构地区 河南师范大学化学化工学院 新乡学院化学与化工学院
出处 《化学研究与应用》 CAS CSCD 北大核心 2014年第11期1758-1763,共6页 Chemical Research and Application
基金 国家自然科学基金(21204019)资助 国家博士后基金(2012M521398)资助 河南省国际科技合作项目(134300510055)资助 河南省重点科技攻关项目(112102310086)资助 河南师范大学青年基金
关键词 毛发状纳米粒子 RAFT聚合 脯氨酸 ALDOL反应 hairy nanoparticle RAFT proline Adol reaction
分类号 O629.7 [理学—有机化学]
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参考文献30

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二级参考文献2

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同被引文献21

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化学研究与应用
2014年 第11期

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