经鼻持续正压通气治疗对合并抑郁焦虑情绪的阻塞性呼吸睡眠暂停综合征患者的影响

Effects of nasal-continuous positive airway pressure on patients with obstructive sleep apnea apnea-hypopnea syndrome combined with depression and anxiety emotions

目的:探讨经鼻持续正压通气(CPAP)治疗对合并情绪障碍的阻塞性呼吸睡眠暂停综合征(OSAHS)患者的影响。方法:选取中重度OSAHS合并情绪障碍患者56例,随机分为CPAP治疗组及常规治疗组,在治疗3月及6月后进行医院焦虑抑郁情绪测量表(HAD量表)评测,比较两组患者之间HAD评分情况。结果:使用CPAP治疗3月后OSAHS患者情绪障碍无明显改善(P>0.05),6月后有明显改善(P<0.01);对照组患者治疗3月及6月后情绪障碍均无明显改善(P>0.05)。结论:对临床上OSAHS合并情绪障碍的患者,经过较长时间CAPA治疗后,其情绪障碍可以得到有效改善。

Objective：To explore effects of nasal-continuous positive airway pressure （ CPAP ） on patients with obstructive sleep apnea apnea-hypopnea syndrome （ OSAHS） combined with depression and anxiety emotions. Methods：56 patients with moder-ate and severe OSAHS with mood disorders were randomly divided into CPAP treatment group and conventional treatment group. The patients were evaluated with HAD test three and six months after the treatment, and the two groups were compared. Results：For CPAP treatment group, the mood disorders were not improved three months after the treatment for the patients with OSAHS （P〉0. 05）;how-ever, they were significantly improved six months after the treatment （P〈0. 01）. For conventional treatment group, the mood disorders were not improved three and six months after the treatment （P〉0. 05）. Conclusions：The state of mood could be improved by effective long-term CPAP therapy for OSAS patients with mood disorders.