双苯并吡喃酮1,3,4-噁二唑基哒嗪酮衍生物的合成

Synthesis of Novel Bichromen-2-one 1,3,4-oxadiazol-pyridazinone

以DMF为溶剂,碳酸钾为催化剂,2-(2H-苯并吡喃-2-酮-3基)-5-巯基-1,3,4-噁二唑与4,5-二氯-2-苄基-哒嗪-3-酮于125℃反应6 h,合成了4-{2-[(2H-苯并吡喃)-2-酮]-1,3,4-噁二唑-5-硫醚}-2-苄基-5-{2-[(2H-苯并吡喃)-2-酮]-1,3,4-噁二唑-5-硫醚}哒嗪-3(2H)-酮化合物,收率68.6%,其结构经1H NMR、IR以及元素分析确证。

Bichromen-2-one 1 ,3 ,4-oxadiazol-pyridazinone in yield of 68.6%was synthesized by the reaction of 3-（5-mercapto-1,3,4-oxadiazol -2-yl） -2H-chromen-2-one with 2-benzyl-4,5-dichloropyridazin -3（2H）-one using K2 CO3 as the catalyst in DMF at 125℃for 6 h.The structure was characterized by 1 H NMR, IR and elemental analysis.