Quadrant微创系统辅助下TLIF与开放TLIF治疗腰椎退行性病变的比较研究

Comparison between Quadrant system assisted TLIF and open TLIF on patients with lumbar degenerative diseases

目的分析Quadrant微创系统辅助下经椎间孔椎间融合术(transforaminal lumbar interbody fusion,TLIF)与开放TLIF治疗腰椎退行性病变的临床效果差异。方法选择在该院接受手术治疗的腰椎退行性病变患者作为研究对象,随机分为接受传统开发TLIF治疗的对照组、接受Quadrant微创系统辅助下TLIF治疗的观察组,比较两组患者的手术相关指标、腰椎功能及疼痛评分及炎症因子水平等差异。结果观察组患者接受微创治疗后的切口长度、术中出血量、术后引流量、术后下地活动时间及总住院时间等指标值均明显小于对照组患者(P<0.05)。观察组患者接受微创治疗后1和3个月的ODI评分低于对照组,JOA评分高于对照组患者(P<0.05)。观察组患者接受微创治疗后的CRP、IL-6、IL-10及TNF-α等水平均明显低于对照组患者(P<0.05)。结论 Quadrant微创系统辅助下TLIF治疗可以减少手术创伤、促进患者术后康复,在缓解患者腰部疼痛的同时提高腰椎功能,降低患者全身炎症水平。

【Objective】To comparably analyzequadrant system assisted TLIF and open TLIF on patients with lumbar degenerative diseases. 【Methods】The patients with lumbar degenerative diseases in our hospitalwere enrolled in the study, randomly divided into control group with open TLIF and observation group with quadrant system assisted TLIF, compared lumbar surgery related indexes, lumbar function and pain scores, inflammatory factors levels.【Results】Observation group patients＇ intraoperative blood loss, postoperative incision length of activity time and total length of hospital stay, postoperative fields such as parameter values were significantly less than that in control group（P〈0.05）. Observation group patients＇ ODI score was lower than that in control group, JOA score was higher（P0.05）. Observation group patients＇ CRP, IL- 6, IL-10 and TNF-α levels were significantly lower（P〈0.05）.【Conclusion】Under the quadrant minimally invasive system auxiliary TLIF treatment can reduce the surgical trauma,promote patients postoperative rehabilitation, and improve the lumbar vertebral function, reduce the level of systemic inflammation.