烟台地区2013年腹泻患儿轮状病毒、肠道腺病毒病原学检测结果分析

Analysis on epidemiological feature of rotavirus and adenovirus infection in children with diarrhea in Yantai area in the year of 2013

目的了解烟台地区2013年婴幼儿腹泻患儿轮状病毒、肠道腺病毒感染情况。方法采用轮状病毒、腺病毒抗原检测试剂盒（乳胶法）对本院门诊及住院腹泻患儿726例粪便进行轮状病毒、腺病毒抗原检测，分析阳性率与性别、年龄及季节的关系。结果726例患儿轮状病毒抗原检出率49．17％，腺病毒抗原检出率7．16％，轮状病毒抗原、腺病毒抗原同时检出3．86％，检出率男女之间不存在差异（P〉0．05），7个月一2岁为感染主要年龄段。结论本地区幼儿腹泻存在较多的轮状病毒感染，腺病毒感染比例相对较低，也存在两种病毒同时感染的情况，年龄和季节对病毒感染阳性率存在影响。

Objective To investigate the epidemiological feature of rotavirus and adenovirus infection in children with diarrhea in Yantai area in the year of 2013. Methods Using detection kit of latex method, rotavirus and adenovirus antigens of 726 feces specimens from children with diarrhea were detected. The relationship between infection rates and gender, age and season were analyzed. Results In all the 726 patients with diarrhea, the positive rate of rotavirus antigen was 49.17%, and that of adenovirus antigen was 7.16%. The coinfection rate of both the two virus was 3.86%. There was no statistically difference between males and females （ P 〉 0.05 ）. The children aged 7 months through 2 years accounted for the most of those infected. Conclusion Rotavirus, more common than adenovirus, are the important pathogen causing child diarrhea in the area of Yantai. In addition to season, age may affect the epidemiological patterns of virus.