期刊文献+

浅谈肠道共生微生物与人类疾病 被引量:1

Human Intestinal Symbiotic Microbes and Human Diseases
下载PDF
导出
摘要 肠道共生微生物与人类健康和疾病密切相关。早期微生物暴露对肠道菌群的定植模式及以后生命过程中疾病的易患性产生深远影响。肠道菌群失调也是一些疾病的症状或诱发原因,比如过敏、肥胖、糖尿病甚至精神疾病。深入研究人类共生微生物与健康和疾病的关系,将为一些疾病的预防和治疗手段提供指导和方向。 The intestinal symbiotic microbes are closely associated to human health and diseases.Early microbial exposure has a long-term influence on intestinal colonization patterns and risk of diseases later in life.The imbalance of the intestinal microbiota is the symptom of some diseases or inductive causes,such as allergies,obesity,diabetes,and even mental illness.Further study of the relationship between symbiotic microbes and human health will provide new methods to prevent and treat some diseases.
出处 《医学综述》 2014年第20期3670-3673,共4页 Medical Recapitulate
关键词 肠道微生物 肠道定植 免疫 代谢 心理精神 Symbiotic microbes Intestinal colonization Immunity Metabolism Mentality
  • 相关文献

参考文献37

  • 1B(a)ckhed F,Ley RE,Sonnenburg JL,et al.Host-bacterial mutualism in the human Intestine[J] .Science,2005,307 (5717):1915-1920.
  • 2Dongqian Shen,Chuan Liu,Ran Xu,et al.Human gut microbiota:dysbiosis and manipulation[J] .Front Cell Infect Microbiol,2012,2:123.
  • 3Sudo N,Sawamura S,Tanaka K,et al.The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction[J] .J Immunol,1997,159(4):739-745.
  • 4Round JL,Lee SM,Li J,et al.The Toll-like receptor 2 pathway establishescolonization by a commensal of the human microbiota[J] .Science,2011,332 (6032):974-977.
  • 5Bashir ME,Louie S,Shi HN,et al.Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy[J] .J Immunol,2004,172 (11):6978-6987.
  • 6Masmanian SK,Liu CH,Tzianabos AO,et al.An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system[J] .Cell,2005,122 (1):107-118.
  • 7Ivanov II,Atarashi K,Manel N,et al.Induction of intestinal Th17 cells by segmented filamentous bacteria[J] .Cell,2009,139 (3):485-498.
  • 8Atarashi K,Tanoue T,Shima T,et al.Induction of colonic regulatory T cells by indigenous Clostridium species[J] .Science,2011,331 (6015):337-341.
  • 9Blaser M J,Falkow S.What are the consequences of the disappearing human microbiota?[J] .Nat Rev Microbiol.,2009,7 (12):887-894.
  • 10Russell SL,Gold M J,Hartmann M,et al.Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma[J] .EMBO Rep,2012,13(5):440-447.

共引文献15

同被引文献20

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部