晚期胃癌维持治疗现状

Maintenance treatment of advanced gastric cancer

晚期胃癌具有复发率高、病死率高的特点,为了延长患者生命、提高生活质量,许多学者提出了维持治疗的理念。目前常用的维持治疗药物是5-fu类制剂:希罗达及替吉奥,但许多患者常因毒副反应大及经济负担重而被迫停药。替加氟作为二代5-fu类制剂,疗效确切、价格低廉,联合中药健脾解毒通络,对晚期胃癌患者的维持治疗大有裨益。

Advanced gastric cancer had the characteristics of high recurrence rate and high mortality.In order to prolong life of patients and improve the quality of life,many scholars put forward the concept of maintenance therapy.The common drugs for maintenance therapy were 5-fu preparations：Xeloda and Gio,but many patients were often forced to withdraw drugs due to the strong side effects and large economic burden.As the second-generation 5-fu preparation,tegafur was effective and inexpensive and it had great benefit to the maintenance treatment of patients with advanced gastric cancer combined with Jianpijiedutongluo of TCM.