立体定向放射治疗Ι期非小细胞肺癌的临床研究进展

The research progress on stereotactic body radiation therapy for stageⅠnon-small cell lung cancer

目前体部立体定向放射治疗（ Stereotactic body radiation therapy ，SBRT）越来越多地应用于无法手术早期非小细胞肺癌患者的治疗，有替代外科作为标准治疗手段的趋势。大量临床研究结果显示SBRT治疗早期肺癌是安全的，临床局部控制率达到90％以上。本文对SBRT治疗Ⅰ期非小细胞肺癌的临床研究进展做一综述。

Image guided stereotactic body radiation therapy （ SBRT） has emerged as a promising technolo-gy for early-stage non-small cell lung cancer （ NSCLC） increasingly ,particularly for patients that are unable to tolerate or deny operation ,with a trend to replace surgical resection .Abundant clinical research results have dem-onstrated that SBRT is safe to yield local control rate of more than 90%without excessive toxicity in early -stage NSCLC.In this review ,we discuss the research progress on treating stage I NSCLC with SBRT .