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肺癌侵犯上腔静脉临床特点及手术治疗策略

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摘要 目的通过分析肺癌侵犯上腔静脉的临床特点,探讨其外科手术治疗策略,以提高临床疗效。方法回顾性分析该院50例肺癌侵犯上腔静脉患者的临床资料,总结手术方式与病理类型、发病情况及术前辅助化疗情况的相关性,分析上腔静脉阻断时间、上腔静脉压力测定情况,并观察术后临床疗效及并发症情况,随访观察患者生存情况。结果手术方式采用以人工血管置换术最多,与其相关的病理类型SCLC多于NSCLS,相比差异有统计学意义(P〈0.05);发病情况初治者少于复发者,相比差异有统计学意义(P〈0.05);术前有辅助化疗者明显少于无辅助化疗者,二者相比差异有统计学意义(P〈0.01);自体修补术上腔静脉阻断时间为3~15min,人工血管置换术阻断时间8~35min,相比差异有统计学意义(P〈0.05);术前人工置换术压力虽高于自体修补术,但差异无统计学意义(P〉0.05);而术中差异有统计学意义(P〈0.05);术后患者上腔静脉压迫症状消失或基本缓解,临床疗效显著;术后发生心律失常、肺炎、肺不张及吻合口出血并发症,但通过治疗均治愈;患者1年生存率为58%,3年生存率为28%;且手术差异无统计学意义(P〉0.05),术前有无辅助化疗差异有统计学意义(P〈0.05)。结论外科手术治疗肺癌侵犯上腔静脉者,临床效果显著,可提高患者生活质量,延长生存期,且术前化疗更有助于疗效提高,临床值得推广。
作者 常博
出处 《中国煤炭工业医学杂志》 2014年第10期1571-1573,共3页 Chinese Journal of Coal Industry Medicine
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