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恶性大脑中动脉梗死治疗研究进展 被引量:2

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摘要 恶性大脑中动脉梗死由Hacke于1996年提出,是颈内动脉远端或大脑中动脉主干血栓形成或栓塞引起的大脑中动脉供血区大面积梗死,CT提示脑梗死范围>1/2大脑中动脉供血区或核磁弥散加权像提示脑梗死体积>145 mL,形成明显的水肿、占位效应,导致神经功能的快速恶化[1~3]。其临床表现为最初2d逐渐出现意识障碍、昏迷,2~4d出现颞叶沟回疝、脑干受压,导致死亡。发病率占幕上脑梗死的1%~10%,保守治疗的病死率高达80%,早期行去骨瓣减压术可明显降低病死率并改善功能预后。然而在恶性大脑中动脉梗死的治疗方面,尚缺乏足够的证据制定合适的治疗方案,现就目前恶性大脑中动脉梗死的治疗现状作一综述。
出处 《山东医药》 CAS 2014年第36期99-102,共4页 Shandong Medical Journal
基金 国家自然科学基金资助项目(81271309) 北京市卫生系统高层次卫生技术人才培养计划项目(2009-3-09)
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