椎动脉发育不良与后循环缺血性卒中:从假说到发病机制

Vertebral Artery Hypoplasia and Posterior Circulation Ischemic Stroke:from Hypothesis to Pathogenesis

椎动脉发育不良是临床常见的后循环血管变异。已有的研究结果显示,椎动脉发育不良是后循环缺血性卒中的危险因素,并与之存在区域性关联。椎动脉发育不良在后循环缺血性卒中的发生发展中起到重要作用。本文对椎动脉发育不良与后循环缺血性卒中之间的关系以及潜在的发病机制进行综述,以期为后循环缺血性卒中的科学预防和临床治疗提供参考。

Vertebral artery hypoplasia is a frequent vascular variation of posterior circulation. Emerging evidence suggests that vertebral artery hypoplasia is a risk factor of posterior circulation ischemic stroke, with a morphological correlation between them. This article reviews research progress of vertebral artery hypoplasia and its role in posterior circulation ischemic stroke in order to promote optimization during clinical decision making.