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右美托咪定对带状疱疹患者后遗神经痛及T细胞分化抗原水平的影响

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摘要 目的探讨右美托咪定对带状疱疹患者后遗神经痛及T细胞分化抗原CD4、CD8、CD4/CD8水平的影响。方法选取90例带状疱疹后遗神经痛患者随机分为两组,各45例。对照组给予甲钴胺、2%利多卡因、地塞米松疼痛点皮内注射等治疗,观察组在此基础上加用右美托咪定,比较治疗前、治疗后15 d神经痛程度(VAS评分)及CD4、CD8、CD4/CD8水平变化。结果治疗后15 d两组患者VAS评分均较治疗前下降(P<0.01);观察组下降更为明显(P<0.01)。治疗后15 d观察组CD4与CD4/CD8较治疗前升高(P<0.05)、CD8较治疗前下降(P<0.05);治疗后15 d两组比较,观察组CD4与CD4/CD8高于对照组(P<0.01),CD8低于对照组(P<0.01)。结论右美托咪定局部注射治疗有助于减轻带状疱疹后遗神经痛患者疼痛程度,并可增强免疫功能。
作者 覃雄 邓亚玲
出处 《白求恩医学杂志》 2014年第5期468-469,共2页 Journal of Bethune Medical Science
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