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淋巴细胞主动免疫在妇产科领域的应用

Lymphocyte active immunization application in the field of obstetrics and gynecology
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摘要 20世纪80年代起,淋巴细胞主动免疫诱导母体妊娠期免疫耐受研究的开展,随之而来的原因不明性反复自然流产(unexplained recurrent spontaneous abortion,URSA)患者成功妊娠,无疑为URSA的治疗带来了福音。这个治疗在很长一段时间内也一直是存在争议的话题。随着近年来生殖医学的迅速发展,由免疫因素造成的不孕成为妇产科领域研究的热点。淋巴细胞主动免疫随之拓展到胚胎反复植入失败(recurrent implantation failure,RIF)和不孕症的治疗当中。 In the 1980 s, the development of lymphocyte active immunization inducing maternal pregnancy immune tolerance research, followed by a successful pregnancy of unexplained recurrent spontaneous abortion (URSA) patients, there is no doubt for the treatment of URSA. This treatment has been the subject of debate for a long time. With the rapid development of reproductive medicine in recent years, infertility caused by immune factors have became the hotspot in research of obstetrics and gynecology. Lymphocyte active immunization correspondingly extend to the treatment of embryos recurrent implantation failure (RIF) and infertility.
作者 林慧 段金良
机构地区 解放军第
出处 《中国优生与遗传杂志》 2014年第10期148-150,146,共4页 Chinese Journal of Birth Health & Heredity
基金 广西科学研究与技术开发计划项目
关键词 淋巴细胞主动免疫 URSA RIF 不孕症 Lymphocyte activeimmunization URSA RIF Infertility
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  • 1Taylor C, Faulk WP. Prevention of recurrent abortion with leucocyte transfusion[J]. Lancet, 1981,11 (1) :68-70.
  • 2Rezaei A, Dabbagh A1. T-help (1)cytokines increase during early pregnancy in women with a history of recurrent spontaneous abortion[J].Med Sci Monit, 2002,8 (8) :CR607-610.
  • 3Wilczygski JR, Radwan P, Tch6rzewski H, Banasik M. Immunotherapy of patients with recurrent spontaneous miscarriage and idiopathic infertility :does the immunization-dependent Th2 cytokine overbalance really matter?[J]. Arch Immunol Ther Exp (Warsz),2012,60 (2) :151-60.
  • 4杨清,游泽山,黄珈,李再仪,彭软.主动免疫治疗对不明原因反复自然流产患者NK细胞的影响[J].中山大学学报(医学科学版),2007,28(B06):234-236. 被引量:3
  • 5Hunt JS, Morales PJ, Pace JL, Fazleabas AT, Langat DK. A commentary on gestational programming and functions of HLA-G in pregnancy[J]. Placenta, 2007, 28 (Suppl A) :S57-S63.
  • 6Winger EE, Reed JL. Treatment with tumor necrosis factor inhibitors and intravenous immunoglobulin improves live birth rates in women with recurrent spontaneous abortion[J]. Am J Reprod Immunol, 2008, 60 (1) :8-16.
  • 7Perricone R, De Carolis C, Kroeler B, et al. Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus rythematosus and recurrent spontaneous abortion[J]. Rheumatology (Oxford), 2008,47 (5) :646-651.
  • 8Zammiti W, Mtiraoui N, Khairi H, et al. Associations between tumor necrosis factor-alpha and lymphotoxin-alpha polymorphisms and idiopathic recurrent miscarriage[J]. Reprod, 2008, 135 (3) : 397-403.
  • 9陈巧儿,秦卫兵,杨宁,叶嘉玲,王一峰,曾少颜,陈瑞玲,欧汝强.免疫治疗原因不明反复自然流产后Th1/Th2型细胞因子和NK细胞的变化[J].中国妇幼保健,2005,20(20):2637-2639. 被引量:10
  • 10董瑞英,史桂芝,许燕雪,江森.不明原因习惯性流产患者主动免疫治疗前后Th1/Th2型细胞因子水平的变化[J].上海免疫学杂志,2003,23(6):410-413. 被引量:12

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