颈髓损伤患者医院获得性肺炎的影响因素分析

Analysis of influence factors of hospital acquired pneumonia in patients with cervical spinal cord injury

回顾性分析478例颈髓损伤患者的病例资料,根据是否发生医院获得性肺炎（HAP）,分为感染组（122例）和非感染组（356例）.以是否发生HAP为因变量,以单因素分析时有统计学意义的变量为自变量,进行logistic多元回归分析,探讨颈髓损伤患者发生HAP的影响因素.结果显示,122例出现HAP（25.52％）;感染组和非感染组在损伤节段、入院时日本骨科协会评估治疗分数（JOAS）、伤后8h内甲泼尼龙注射液治疗情况、气管切开、吸烟史和肺部疾病病史比较,差异有统计学意义（P＜0.05）;损伤节段（OR =4.474）、入院时JOAS（OR=3.856）、气管切开（OR=2.452）和肺部疾病病史（OR=1.589）均为颈髓损伤患者HAP的独立影响因素.

To explore the influence factors of hospital acquired pneumonia （HAP） in patients with cervical spinal cord injury（CSCI）.Regression analysis the clinical data of 478 cases of patients with CSCI,the CSCI patients were divided into the infection group and non-infection group.Firstly,the single factor analysis was used to compare the difference of the influence factors between the two groups.And then,logistic regression analysis was used to explore the influence factors of HAP in patients with CSCI.122 suffered HAP in the 478 patients with CSCI,accounted for 25.52%.There＆#39;s significant difference in injured segments,JOAS scores on admission,methylprednisolone treatment within 8 h after injury,tracheotomy,history of smoking and lung disease between the infection group and non-infection group（P 〈 0.05）.logistic regression analysis showed that the injured segments （OR =4.474）,JOAS scores on admission （OR =3.856）,tracheotomy （OR =2.452）,history of lung disease （OR =1.589） were the independent influence factors of HAP in patients with CSCI.The incidence rate of HAP was high in patients with CSCI,there were a variety of influence factors for the HAP,and we should take targeted intervention measures so as to reduce the incidence of HAP.