糖尿病并发高尿酸血症与血脂及血压的相关性分析

Correlation analysis of blood pressure and blood lipids and diabetes mellitus combined with hyperuricemia

目的分析血脂及血压(BP)与糖尿病(DM)并发高尿酸血症(HUA)的相关性。方法分别抽选2型糖尿病(T2DM)+HUA者、T2DM者、HUA患者、健康体检者,均50例,分别记为A、B、C、D组。测量研究对象的血脂和血压水平。结果 A组与D组比较,以及B组与D组比较,收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)差异具有统计学意义(P<0.05);C组与D组比较,SBP、TG、TC、LDL、HDL差异具有统计学意义(P<0.05);A组与B组比较,以及A组与C组比较,SBP、TG、TC差异具有统计学意义(P<0.05)。结论伴有HUA的T2DM患者存在血压和血脂升高的危险因素,治疗过程中应在控制血糖的基础上加以控制,及时给予治疗干预。

Objective To analyze the correlation of blood pressure （BP）, blood lipid and diabetes mellitus （DM） combined with hyperuricemia （HUA）. Methods Patients with type 2 Diabetes Mellitus （T2DW）＋HUA, T2DW, HUA and healthy patients were selected as group A, group B, group C, and group D. 50 cases in each group. Levels of blood lipid and blood pressure were measured. Results Comparisons between groups A and D, and between groups B and D showed that the differences of systolic blood pressure （SBP）, diastolic blood pressure （DBP）, triglyceride （TG）, total cholesterol （TC）, low density lipoprotein （LDL）, and high density lipoprotein （HDL） had statistical significance （P〈0.05）. Comparing group C and D, the differences of SBP, TG, TC, LDL, and HDL had statistical significance （P〈0.05）. Comparisons between groups A and B and between groups A and C showed that SBP, TG, and TC had statistical significance in the differences （P〈0.05）. Conclusion Patients with T2DW and HUA have risk factors for blood pressure and blood lipids elevation. Control and timely therapeutic intervention should be applied during glycemic control.