国产头孢美唑治疗细菌感染有效性和安全性的Meta分析

Meta analysis of the efficacy and safety of domestic cefmetazole in the treatment of bacterial infections

目的探讨国产头孢美唑治疗细菌感染的有效性和安全性。方法制定原始文献纳入和排除标准及检索策略,检索文献数据库,收集国产与进口头孢美唑治疗细菌感染的随机对照试验研究报告,提取文献数据定量综合分析。结果国产与进口头孢美唑治疗细菌感染有效率OR=1.12,不良反应率OR=0.91。结论国产头孢美唑治疗细菌感染有效性和安全性与进口相当,治疗细菌感染安全有效。

Objective To explore the efficacy and safety of domestic cefmetazole in the treatment of bacterial infection. Methods The original literature inclusion and exclusion criteria and the search strategy were established to search document database for the randomized controlled trial reports of domestic and imported cefmetazole in treatment of bacterial infection. The literature data were used for quantitative and comprehensive analysis. Results The effective rate OR value of domestic and imported cefmetazole in treatment of bacterial infection was 1.12, and the adverse reaction rate OR value was 0.91. Conclusion Domestic cefmetazole in the treatment of bacterial infection have the similar efficacy and safety with imported cefmetazole, and it is a safe and effective treatment of bacterial infection.