摘要
BackgroundFew 研究在跟随 non-ST-elevation 的治疗的生活(HRQL ) 的健康相关的质量比较了变化有经皮的冠的干预(一种总线标准) 或冠的动脉的急性冠的症候群(NSTE 交流) 绕过 grafting (CABG ) 。这研究是在在医院以后的六个月在经历了任何一个一种总线标准的 NSTE 交流病人之间解除的 HRQL 比较变化或 CABG.MethodsHRQL 与 NSTE 交流在 1012 个连续病人在分泌物以后在承认和六个月用西雅图咽峡炎问询表被估计。为了与 HRQL 估计一种总线标准和 CABG 的协会,变化,当 PCI 和 CABG 组织的依赖 variables.ResultsAlthough 在 6 月的后续经历了咽峡炎地势和另外的改进,逻辑回归模型被构造在西雅图咽峡炎问询表的每种尺寸的分数对待变化(P <;0.001 ) ,相对一种总线标准组的 CABG 在咽峡炎频率显示出更重要的改进(P = 0.044 ) 并且生活的质量(P = 0.028 ) 。在 multivariable 逻辑分析, CABG 也是为咽峡炎频率的改进的一个独立预言者(或:1.62, 95%CI:1.09 −; 4.63, P = 0.042 ) 并且生活的质量(或:2.04, 95%CI:1.26 −; 6.92, P = 0.038 ) 相对有 NSTE 交流的 PCI.ConclusionsIn 病人,一种总线标准和 CABG 在六个月在疾病特定的健康地位提供大改进,与以咽峡炎频率和生活的质量是更突出的 CABG 的。
BackgroundFew studies have compared change in the health-related quality of life (HRQL) following treatment of non-ST-elevation acute coronary syndrome (NSTE-ACS) with either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). This study is tocompare changes in HRQL six months after hospital discharge between NSTE-ACS pa-tients who underwent either PCI or CABG.Methods HRQL was assessed using the Seattle angina questionnaire at admission and six months after discharge in 1012 consecutive patients with NSTE-ACS. To assess associations of PCI and CABG with HRQL changes, logistic regression models were constructed treating changes in the score of each dimension of the Seattle angina question-naire as dependent variables.Results Although both the PCI and CABG groups experienced angina relief and other improvements at 6-month follow-up (P〈0.001), the CABG relative to PCI group showed more significant improvements in angina frequency (P= 0.044) and quality of life (P= 0.028). In multivariable logistic analysis, CABG also was an independent predictor for both im-provement of angina frequency (OR: 1.62, 95%CI: 1.09-4.63,P= 0.042) and quality of life (OR: 2.04, 95%CI: 1.26-6.92,P= 0.038) relative to PCI.Conclusions In patients with NSTE-ACS, both PCI and CABG provide great improvement in disease-specific health status at six months, with that of CABG being more prominent in terms of angina frequency and quality of life.