肺癌呼吸道菌群失调导致二重感染

Respiration Tract Bacteria Groups Inbalance Result in Lung Cancer Combine Dualistic Infection

目的探讨肺癌合并二重感染的治疗及早期诊断以改善预后。方法回顾性研究2006年8月至2013年12月住院患者43例二重感染患者的临床特征,治疗及预后。结果随着广谱抗生素,抗肿瘤药物,皮质激素,化疗药物的广泛应用,发病率有增高趋势,43例均有此病史,病死率极高,达27,9%(12/43)。结论常发生在呼吸道菌群失调,机体防御功能明显降低的情况下,尽可能早期诊断和早期治疗有助于降低病死率,同时了解致病菌种和药敏结果,可以指导临床用药合理性。

Objeetive Study on early diagnosis, therapy and prophylaxis for lung cancer combine dualistic infection .Methods Retrospective study of the clinical feature.treatment and outcome of 43patients with lung cancer combine dualistic infection.from August 2006 to December 2013. ResuIt Priorantimierobial therapy. Steroids/cytotoxic therapy. The morbidity more increase all 43 patients had same history, the mortality of was very high was 27.9%（12/43）. Conlusion Happen usually under respiration tract bacteria groups inbalance, body defence function reduce circumstances, early diagnosiS and therapy contribute to reduce mortality. It’s benifitial for guiding clinical treatment to reeongine specie and antibacteria1 susceptibi1ity test of pathogenic becteria.