老年患者外周静脉置入中心静脉导管置管后导管相关性血栓发生情况分析

Incidence of PICC-related venous thrombosis in elderly patients

目的调查老年患者进行外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)置管后,导管相关性静脉血栓发生情况;比较不同年龄阶段、不同导管留置时间下静脉血栓的发生率,并分析血栓发生的危险因素,为老年患者PICC置管后血栓并发症的预防提供指导。方法选取2008年1月-2012年12月在我院老年病房住院并进行PICC置管的393例患者,对其性别、年龄、基础疾病、置管部位、导管留置时间、血栓发生情况进行回顾性分析。结果 393例中50例(12.72%)发生导管相关性血栓并发症;老年患者PICC导管相关性血栓的发生与导管留置时间和年龄并无直接关系(P>0.05);将血栓组和非血栓组的血栓发生危险因素进行比较,两组之间的静脉血栓病史有统计学差异(P<0.01)。结论PICC导管相关性血栓在老年患者中仍有较高的发生率;静脉血栓病史是预测老年患者PICC导管相关性血栓发生的重要危险因素。

Objective To investigate and compare the incidence rate of peripherally inserted central catheter （PICC） related venous thrombosis among elderly patients of different ages and catheter retention time,analyze the risk factors and provide guidance for the prevention of PICC-related thrombosis.Methods Three hundred and ninety-three hospitalized elderly patients （age,67-98 years old） admitted to our hospital from January 2008 to December 2012 who underwent PICC operation were selected,and their basic diseases,catheterization location,catheter retention time and occurrence of thrombosis were retrospectively analyzed.Results Of the 393 patients,50 cases （12.72％） were found to have PICC-related thrombosis.The occurrence of PICC-related thrombosis was not associated with age and catheter retention time among elderly patients （P ＞ 0.05）.There was significant difference between thrombosis group and non-thrombosis group in the comparison of venous thrombosis history （P ＜ 0.01）.Conclusion A high ratio is found on the incidence rate of PICC related-venous thrombosis in elderly patients,and venous thrombosis history is an important risk factor to predict the occurrence of PICC-related thrombosis.