宫颈冷刀锥切术及冰冻病理检查在宫颈上皮内瘤变(CIN)Ⅲ诊断治疗中的应用分析

The Analysis of Cold Knife Conization and Frozen Section Examination for Diagnosis and Treatment of the Cervical Intraepithelial Neoplasia Ⅲ

目的探讨宫颈冷刀锥切术及冰冻病理检查在宫颈上皮内瘤变(CIN)Ⅲ诊治中的价值。方法总结分析我院宫颈活检诊断为CINⅢ的患者60例,行宫颈冷刀锥切术及将标本术中冰冻病理检查,根据冰冻病检结果,决定仅行宫颈冷刀锥切术或筋膜外全子宫切除术或宫颈癌根治术。比较术前宫颈活检、术中冰冻病检、术后标本石蜡病理检查之间的符合率。结果术前宫颈活检与术中冰冻病检符合率为65%(39/60),术中冰冻病检与术后石蜡病理检查报告符合率为96.67%(58/60)。结论宫颈冷刀锥切联合术中冰冻病检是进一步诊断、指导治疗CINⅢ的快速、准确的方法。

Objective To study the role of cold knife conization（ CKC） and frozen section examination（ FSE） for diagno-sis and treatment of cervical intraepithelial neoplasia III（ CINIII） . Methods Collected 60 patients with a preoperative biopsy re-sult of stage CINIII were underwent CKC and FSE. By the result of FSE,to planned the operation such as cold knife conization or hysterectomy or operation for invasive cervical cancer. Compliance rate were comparaed with preoperative biopsy result and CKC, CKC and permanent section. Results The compliance rate between preoperative biopsy and cold knife conization was 65%. The compliance rate between cold knife conization and permanent section was 96. 67%. Conclution Cold knife conization and frozen section examination is a rapid and reliable method for diagnosis and treatment of cervical intraepithelial neoplasia III farther.