期刊文献+

糖尿病足患者多药耐药菌感染的危险因素分析 被引量:6

Risk factors for multidrug-resistant bacteria infections in diabetic foot patients
原文传递
导出
摘要 目的研究糖尿病足患者多药耐药菌发生原因,分析多药耐药菌感染的危险因素,以降低多药耐药菌感染。方法对2010年5月-2013年5月医院内分泌科与骨科收治的160例糖尿病足感染患者送检标本进行培养,并对检出病原菌及其药敏结果进行分析;研究糖尿病足患者多药耐药菌感染的危险因素。结果 160例糖尿病足感染患者中有51例发生多药耐药菌感染,占31.8%,分离出75株多药耐药菌,其中金黄色葡萄球菌、铜绿假单胞菌及肠杆菌科高居前3位,分别占40.0%、25.4%及24.0%;通过多因素logistics回归分析显示,既往的抗菌药物暴露史、暴露时间、因同一处部位感染住院>2次/年、合并骨髓炎以及神经缺血性伤口等是发生多药耐药菌感染危险因素。结论糖尿病足患者发生多药耐药菌感染与多种因素有密切的关系,临床医师应该采取相应措施加以控制。 OBJECTIVE To explore the causes of multidrug-resistant bacteria infections in the patients with diabetic foot and analyze the risk factors for the multidrug-resistant bacteria infections so as to reduce the incidence of multidrug-resistant bacteria infections .METHODS A total of 160 patients with diabetic foot infections who were treated in the department of endocrinology and department of orthopedics from May 2010 to May 2013 were enrolled in the study ,then the submitted specimens were cultured for the isolation of pathogens ,the results of the drug susceptibility testing for the isolated pathogens were analyzed ,and the risk factors for the multidrug-resistant bacteria infections in the diabetic foot patients were observed .RESULTS Of the 160 patients with diabetic foot ,51 cases were infected with the multidrug-resistant bacteria ,accounting for 31 .8% .Totally 75 strains of multidrug-resistant bacteria have been isolated ,among which the Staphylococcus aureus ,Pseudomonas aeruginosa ,and En-terobacteriaceae ranked the top three species ,accounting for 40 .0% ,25 .4% ,and 24 .0% ,respectively .The multivariate logistic regression analysis indicated that the history of exposure to antibiotics ,time of exposure , frequency of hospitalization more than twice a year due to the same site infections ,complication of osteomyelitis , and neurological ischemic wounds were the risk factors for the multidrug-resistant bacteria infections . CONCLUSIONS The incidence of the multidrug-resistant bacteria infections in the diabetic foot patients is closely related to multiple factors ,and the clinicians should take corresponding control measures .
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2014年第21期5344-5346,共3页 Chinese Journal of Nosocomiology
基金 黑龙江省教育厅基金项目(12531812)
关键词 糖尿病足 多药耐药菌 感染 危险因素 Diabetic foot Multidrug-resistant bacteria Infetion Risk factor
  • 相关文献

参考文献4

  • 1Amini N,Alavian SM,Kabir A,et al.Clinical features and seroepidemiology of anti-HDV antibody in patients with chronic Hepatitis B Virus Infection in Iran:A meta-analysis[J].Hepat Mon,2011,11(12):960-967.
  • 2梁丽荣,赵维彦,邱旭东,吕悦,梁美荣.糖尿病足部感染的病原菌分布及耐药性分析[J].中国实验诊断学,2012,16(3):516-517. 被引量:6
  • 3Ohsawa M,Kato K,Itai,et al.Standardized prevalence ratios for chronic hepatitis C virus infection among adult Japanese hemodialysis patients[J].Journal of epidemiology,2010,20(1):30-39.
  • 4Magnus MC,Vestrheim DF,Nystad W,et al.Decline in early childhood respiratory tract infections in the norwegian mother and child cohort study after introduction of pneumococcal conjugate vaccination[J].The Pediatric infectious disease journal,2012,31(9):1212-1216.

二级参考文献4

共引文献5

同被引文献80

  • 1Graziani L.Comprehensive approach to management of critical limb ischemia[J].Curr Treat Options Cardiovasc Med,2014,16(9):332.
  • 2Bravo-Molina A,Linares-Palomino JP,Lozano-Alonso S,et al.Influence of microbiology and wound scores in the the diabetic foot syndrome outcome[J].European Journal of Vascular and Endovascular Surgery,2014,48(3):346-347.
  • 3Chu Y,Wang C,Zhang J,et al.Can We Stop Antibiotic Therapy When Signs and Symptoms Have Resolved in Diabetic Foot Infection Patients?[J].Int J Low Extrem Wounds,2015,14(3):277-283.
  • 4Forsythe RO,Brownriqq J,Hinchliffe PJ,et al.Peripheral arterial disease and revascularization of the diabetic foot[J].Diabetes Obes Metab,2015,17(5):435-444.
  • 5Alvaro-Afonso FJ,Lázaro-Martinz JL,Aragón-Sánchez J,et al.What Is the Clinical Utility of the Ankle-Brachial Index in Patients With Diabetic Foot Ulcers and Radiographic Arterial Calcification?[J].Int J Low Extrem Wounds,2015,14(4):372-376.
  • 6Khalil MA,Kim HK,Hoj JW,et al.Detection of Peripheral Arterial Disease Within the Foot Using Vascular Optical Tomographic Imaging:A Clinical Pilot Study[J].Eur J Vasc Endovasc Surg,2015,49(1):83-89.
  • 7D’Souza M,Kulkarni V,Bhaskaran U,et al.Diabetic Peripheral Neuropathy and its Determinants among Patients Attending a Tertiary Health Care Centre in Mangalore,India[J].J Public Health Res,2015,4(2):450.
  • 8Bril V,Buchanan RA.Long-term effects of ranirestat(AS-3201)on peripheral nerve function in patients with diabetic sensorimotor polyneuropathy[J].Diabetes Care,2006,29(1):68-72.
  • 9Kim HR,Han SK,Rha SW,et al.Effect of percutaneous transluminal angioplasty on tissue oxygenation in ischemic diabetic feet[J].Wound Repair Regen,2011,19(1):19-24.
  • 10Zafarghandi MR,Nazari I,Taghavi M,et al.Long term effects of below-the-knee angioplasty in diabetic patients with critical ischemia of lower limbs referred to Sina Hospital during 2010-2011[J].Pol Przegl Chir,2014,86(12):555-562.

引证文献6

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部