紫杉醇治疗60例妇科恶性肿瘤的临床疗效

The clinical efficacy of 60 cases of gynecological malignancies treated with paclitaxel

目的探究与分析紫杉醇治疗妇科恶性肿瘤的临床疗效。方法选取我院2012年5月~2014年5月收治的60例妇科恶性肿瘤患者,采取随机数字表法分为A组、B组及C组,A组仅给予紫杉醇治疗,B组给予紫杉醇联合卡铂治疗,C组给予紫杉醇联合异环磷酰胺治疗。观察三组患者的临床疗效。结果 A组患者总有效率为40.00%;B组患者总有效率为60.00%;C组患者总有效率为50.00%,C组患者的总有效率明显高于A组（χ2=4.34,P〈0.05）,B组患者的总有效率明显高于C组（χ2=4.25,P〈0.05）。结论采用紫杉醇治疗妇科恶性肿瘤的疗效显著,联合卡铂的疗效更为突出,能够提升患者的生存质量,且为一种理想的治疗方案。

Objective To explore the clinical effiency of gynecologic malignancies and analyse paclitaxel. Methods A total of 60 cases of patients were treated with gynecologic malignancies In our hospital from May 2012 to May 2014 , randomly divided into group A, group B and group C,those in A group only given paclitaxel therapy,and those in group B received paclitaxel plus carboplatin,while those in group C plused paclitaxel and ifosfamide treatment, observing the clinical effiency of three groups of patients. Results A group total effective rate was 40.00%; Group B patients with to- tal effective rate was 60.00%; group C patients with total effective rate was 50.00%. Concluded by the statistic, the ef- fective rate in group C was significantly higher than that in group A. The total effective rate in group B was significant- ly higher than that in group C patients （P〈0.05）. Conclusion Taxol treatment of gynecological malignancies lave signifi- cant effect. Combining with cisplatin for better efficacy prominent can improve the quality of life of patients, which can be an ideal treatment plan.