一起鼠型斑疹伤寒爆发疫情中患者血清恙虫病抗体检测

Detection of antibody against scrub typhus in sera from patients in an outbreak of murine typhus

目的筛查一起鼠型斑疹伤寒爆发疫情患者血清中恙虫病抗体。方法用间接免疫荧光法对20份爆发疫情病人血清进行鼠型斑疹伤寒和恙虫病IgG抗体检测。结果 20例患者中,鼠型斑疹伤寒抗体阳性13例,阳性率65%;恙虫病抗体阳性2例(同时鼠型斑疹伤寒抗体阳性),阳性率10%。结论该起鼠型斑疹伤寒爆发疫情患者中存在恙虫病感染,临床上应加强对鼠型斑疹伤寒与恙虫病的诊断与鉴别诊断。

Objective To detect the antibody against scrub typhus in sera from patients in an outbreak of murine typhus. Methods The IgG against murine typhus and scrub typhus from 20 sera samples collected from patients in an outbreak were tested by indirect immunofluoresence assay （IFA）. Results For the 20 cases, 13 cases were positive with IgG antibody against murine typhus （accounting for 65%）, 2 cases were positive with IgG antibody against scrub typhus and murine typhus （accounting for 10%）. Conclusion There were patients infected with chigger simultaneously in this outbreak of murine typhus and it was necessary for medical institutions to enhance the diagnosis and differential diagnosis forscrub typhus and murine typhus.