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耐药基因蛋白在不同分子亚型乳腺癌中的表达及其与雌孕激素受体和人表皮生长因子受体2的关系 被引量:7

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摘要 乳腺癌耐药为多种耐药基因参与、不同机制共同作用的结果,涉及P-糖蛋白(P-gp)、谷胱甘肽-S-转移酶(GST-π)、DNA拓扑异构酶(TOPO-Ⅱ)等.在本研究中,我们探讨了不同分子亚型中乳腺癌耐药基因蛋白的表达及其与激素受体和人表皮生长因子受体2 (human epidermal growth factor receptor 2,HER-2)的关系。
机构地区 南京
出处 《中华肿瘤杂志》 CAS CSCD 北大核心 2014年第10期771-772,共2页 Chinese Journal of Oncology
基金 江苏省自然科学基金(BK20131016) 江苏省333高层次人才培养工程(BRA2011214)
关键词 乳腺肿瘤 多药耐药相关蛋白质类 分子亚型 雌激素受体 孕激素受体 Breast neoplasms Multidrug resistance-associated proteins Molecular subtypes Estrogen receptor Progesterone receptor
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