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药物性肝损伤组织病理学评分再探讨 被引量:6

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摘要 由于肝脏是药物代谢的重要器官,因此随着各种新药的不断涌现,药物性肝损伤(DILI)逐年增多,已知超过600多种药物可引起DILI。DILI的临床表型包括:急性肝炎、慢性肝炎、急性胆汁淤积、慢性胆汁淤积和胆汁性肝炎,DILI肝脏组织病理学变化包括: 1.单纯性黄疸:肝细胞弥漫性胆汁淤积伴毛细胆管扩张,胆栓形成,无肝细胞变性坏死,门管区无炎症反应。
作者 胡锡琪
出处 《肝脏》 2014年第8期577-579,共3页 Chinese Hepatology
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参考文献14

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二级参考文献1

  • 1Dr. Albert J. Czaja MD,Herschel A. Carpenter MD. Validation of scoring system for diagnosis of autoimmune hepatitis[J] 1996,Digestive Diseases and Sciences(2):305~314

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