老年糖尿病患者的管理及药物治疗

Management and drug therapy in elderly patients with diabetes mellitus

当今社会,人口老龄化是世界人口发展的普遍趋势,糖尿病是老年人中常见疾病之一,随着社会生活水平的提高,老年人中糖尿病发病率也在逐年升高,老年糖尿病患者具有症状不典型、并发症多、常伴有慢性心血管疾病、易发生低血糖等特点,对于老年糖尿病患者这个特殊群体,尤其需要安全有效的药物,并且由于个体差异较大,因此很难制定统一的治疗方案,因此需要个体化,目前普遍使用的口服药物包括二甲双胍、胰岛素促分泌剂（磺脲类和非磺脲类）、α-葡萄糖苷酶抑制剂、噻唑烷二酮类和DPP4抑制剂.

Nowadays,aging is the general trend of population development in the world.Type 2 diabetes is one of the most common chronic diseases in the elderly.Because of the atypical symptoms and signs,accompaniment of chronic cardiovascular disease and vulnerability to low blood glucose in the elder patients with diabetes,we should to make safe,effective,and individualized therapeutic programs for them.This paper will review the current prevalence,characteristics,and oral drug selection among elderly individuals with T2DM.