摘要
回顾性分析28例直肠癌患者的磁共振成像(MRI)资料,结合高分辨率MRI(HR-MRI)及弥散加权成像(DWI)的多序列MRI对患者进行T、N分期,并与术后病理对照。术后标本采用CD34单克隆抗体行免疫组化染色计数微血管密度(MVD),统计MRI分期与MVD的关系及表观弥散系数(ADC)与MVD的相关性。结果显示多序列MRI对直肠癌T分期总的正确率为85.7%(24/28),Kappa=0.805;N分期正确率为82.14%(23/28),Kappa=0.632。MRI T3-4期的MVD值(27.00±4.34)较T1-2期(20.47±3.60)高,N1-2期(26.35±4.06)较N0期(19.09±2.98)高,差异有统计学意义。ADC与MVD呈负相关(r=-0.743,P<0.05)。
Magnetic resonance imaging(MRI) data were analyzed retrospectively in 28 patients of rectal cancer, u- sing multiple sequence MRI including high-resolution MRI (HR-MRI) and diffusion weighted imaging (DWI) for TN staging, and compared with postoperative pathological findings. Using the CD34 monoelonal antibody calculated micro-vessel density(MVD) and reached the relationship between MR staging and MVD and the correlation be- tween apparent diffusion coefficient(ADC) and MVD. The result was that the total accuracy rate of MRI T staging was 85.7% ( 24/28 ), Kappa = 0. 805 and N staging was 82. 14% ( 23/28 ), Kappa = 0. 632. The MVD ( 27 ± 4.34) of MR T3-4 was higher than T1-2(20. 47 ±3.60) and N1-2(26. 35 ±4. 06) was higher than No( 19.09 ± 2. 98). The difference had statistical significance. ADC was negatively correlated with MVD ( r = - 0. 743, P 〈 0. 05).
出处
《安徽医科大学学报》
CAS
北大核心
2014年第11期1685-1688,共4页
Acta Universitatis Medicinalis Anhui
基金
安徽省卫生厅医学科研基金(编号:2010B002)