基于肝血管树的三维超声自动图像融合初步研究

A preliminary study of three-dimensional ultrasound images automatic registration based on hepatic vessel

目的 探讨基于肝血管树的三维超声（3DUS）图像自动融合新技术在临床应用的可行性及准确性.方法 应用基于肝血管树3DUS图像融合技术对10例健康志愿者肝进行三维超声容积图像自动融合,数据采集和融合部位包括：左肝外叶、左肝内叶、右肝前叶及右肝后叶各10对三维超声容积数据,共40对,评估该技术在肝上述各部位的成功率及准确性.结果 36对三维超声容积图像自动融合成功,成功率为90％（36/40）,配准误差约1.48 mm（0.98～2.76 mm）;左肝外叶、左肝内叶、右肝前叶及右肝后叶融合成功率差异无统计学意义（P=0.891）,而配准误差右肝前叶小于左肝外叶（P=0.014）.结论 基于肝血管树自动配准的3DUS图像融合技术是可行的,在将来临床应用中具有广阔的前景.

Objective To evaluate the feasibility and accuracy of three-dimensional ultrasound （3DUS） automatic image fusion based on hepatic vessel in clinical application.Methods Forty pairs of 3D ultrasound volumetric images from 10 healthy volunteers were acquired and enrolled in the study,including 10 pairs of each following lobe of the liver：left lateral lobe,left medial lobe,right anterior lobe and right posterior lobe.3DUS automatic registrations were performed based on hepatic vessel.The technical successful rate and accuracy of the image fusion using the 3DUS data from four hepatic lobes were observed and compared.Results Thirty-six pairs of volumetric data were successfully fused together by automatic registration.The technical successful rate was 90% （36/40） and the registration error distance was 1.48 mm （0.98-2.76 mm）.There were no statistical differences in the successful rate for the four different hepatic lobes （P =0.891）,but the registration error of right anterior lobe was less than left lateral lobe of liver （P =0.014）.Conclusions The new technology of 3DUS automatic registration based on hepatic vessel was feasible and reliable,and it has a wide prospect in future clinical application.