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CD68和CD163在结肠肿瘤组织中的表达及意义 被引量:1

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摘要 探讨结肠肿瘤组织中CD68+和CD163+2种巨噬细胞的浸润程度的差异及其临床意义。采用免疫组织化学染色的方法,用CD68和CD163分别标记巨噬细胞,光镜下计数染色阳性细胞数,分别统计并比较两者与结肠癌病理特征的相关度差异。2种标记的巨噬细胞在结肠癌组织中均有较多浸润,且前者多于后者,差异有统计学意义(P=0.01),两者浸润数量均与结肠癌的分化程度呈负相关,与淋巴结转移数量呈正相关,但CD163+巨噬细胞的相关性更大。巨噬细胞在结肠癌的发展中起重要作用,且与其分化程度、淋巴结转移等密切相关,CD163+巨噬细胞的浸润与结肠癌病理特征的关系更为密切。
出处 《中国现代普通外科进展》 CAS 2014年第9期735-736,739,共3页 Chinese Journal of Current Advances in General Surgery
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参考文献9

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二级参考文献5

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