仙丹升血颗粒治疗特发性血小板减少性紫癜的疗效观察

Observation on Efficacy of Xiandan Shengxue Granules in Treating Idiopathic Thrombocytopenic Purpura

目的:观察仙丹升血颗粒治疗特发性血小板减少性紫癜的临床疗效。方法:将123例特发性血小板减少性紫癜的患者随机分为2组,治疗组63例,对照组60例,对照组给予维血宁颗粒,治疗组给予仙丹升血颗粒,疗程为4周,观察紫斑、神疲乏力、五心烦热、口干、出血、血小板计数等各项指标变化。结果:仙丹升血颗粒治疗特发性血小板减少性紫癜显效率为84.13%,总有效率为96.83%,对照组的显效率为85.00%,有效率为95.00%,经统计学处理,组间无统计学意义;对特发性血小板减少性紫癜所致中医证候的显效率为71.43%,总有效率为95.24%,对照组的显效率为66.67%,总有效率为95.00%,无统计学意义;说明2组间疗效相似。结论:仙丹升血颗粒用于特发性血小板减少性紫癜有较好疗效。

Objective： To observe the efficacy of Xiandan Shengxue granules on the treatment of idiopathic thrombocytopenic purpura. Methods： One hundred and twenty three patients with idiopathic thrombocytopenic purpura were randomly divided into treatment group （n = 63 ） and control group （n = 60）. Patients in the control group were given Weixuening granules, and the treatment group applied Xiandan Shengxue granules. The course of treatment was 4 weeks. The changes of purple, god fatigue, five upset hot, dry mouth, bleeding, platelet count were observed. Results： The excellence rate of treatment was 84.13% , and its total effective rate was 96. 83% ; the excellence rate of the control group was 85.00% , and the total effective rate was 95.00%. There was no significant difference between groups. For idiopathic thrombocytopenic purpura caused by traditional Chinese medicine syndrome, the excellence rate of treatment group was 71.43%, and total effective rate was 95.24% ; and excellence rate of the control group was 66.67% , and the total effective rate was 95.00% , there was no significant difference which meant similar curative effect between the two groups. Conclusion： The Xiandan Shengxue granules treating idiopathic thrombocytopenic purpura have good curative effect.