中药治疗癌性疼痛的用药规律分析

Analysis on Composition Principles of Prescription for Cancerous Pain

目的:挖掘临床中药治疗癌性疼痛方剂的用药规律。方法:应用中医传承辅助系统软件,采用该软件集成的规则分析、熵聚类等数据挖掘方法,对期刊全文数据库中中药治疗癌性疼痛方剂的用药规律进行分析。结果:通过筛选,收集明确中药治疗癌性疼痛方剂共92首,中药184味。确定药物出现的频次,药物之间的关联规则,演化得到核心组合7个、新处方7个。结论:中药辨证治疗癌性疼痛以扶正祛邪为主要治则,以补为主,攻补兼施,多用补虚、活血祛瘀、清热解毒之品。

Objective： To analyze the composition principles of prescription for cancerous pain. Methods ： Prescriptions used for cancerous pain on CNKI were retrieved, and the relevant data were entered into the TCM inheritance support system to conduct principle analysis and hierarchical clustering to analyze composing principles. Results： Based on the analysis of 92 eases of prescriptions, including 184 kinds of herbs, the frequency of each herb and association rules among herbs included in the database were computed, and 7 core combinations and 7 new prescriptions were mined from the database. Conclusion： The prescriptions for cancerous pain were based on the principle of ＂strengthening body resistance and eliminating evil＂, with the application of deficiency-tonifying, blood-activating, and heat-clearing drugs.